Karnani Lab focuses on big data analytics and biomarker discovery related to women and child health. We are particularly interested in taking multi-omics approaches (genetics, epigenetics, transcriptomics, lipidomics, microbiomics, metagenomics and metabolomics) by leveraging the bio-samples collected from Singapore’s largest and most comprehensive longitudinal birth cohorts. Omics information from our cohort studies is generated from a variety of tissues and cell types, and most importantly longitudinally providing the dynamics of molecular marks at different stages of pregnancy and child development. We have been integrating the findings from omics data to develop better insights into metabolic diseases (gestational diabetes and child obesity), micronutrient deficiencies and mental health adversities. Our research findings have led to collaborations with nutrition industries, local and international academic institutes, and consortia.